Genetic Drivers of Female Mosaic X Chromosome Loss

Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland

Aoxing Liu, Matti Pirinen, Zhiyu Yang, Mervi Aavikko, Timo P. Sipilä, Awaisa Ghazal, Aarno Palotie, Hanna M. Ollila, Taru Tukiainen, Mark J. Daly & Andrea Ganna

Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA

Aoxing Liu, Aarno Palotie, Mark J. Daly & Andrea Ganna

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA

Aoxing Liu, Hanna M. Ollila, Pradeep Natarajan & Mark J. Daly

Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA

Aoxing Liu, Giulio Genovese, Seyedeh M. Zekavat, Vijay G. Sankaran, Aarno Palotie, Hanna M. Ollila, Pradeep Natarajan, Mark J. Daly, Steven A. McCarroll, Po-Ru Loh & Andrea Ganna

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA

Aoxing Liu, Giulio Genovese, Aarno Palotie, Mark J. Daly, Steven A. McCarroll & Andrea Ganna

Department of Genetics, Harvard Medical School, Boston, MA, USA

Giulio Genovese & Steven A. McCarroll

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK

Yajie Zhao, Katherine A. Kentistou, Eugene J. Gardner & John R. B. Perry

Department of Public Health, University of Helsinki, Helsinki, Finland

Matti Pirinen

Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland

Matti Pirinen

Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA

Seyedeh M. Zekavat & Pradeep Natarajan

Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA

Seyedeh M. Zekavat

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA

Kai Yu, Derek W. Brown, Weiyin Zhou, Wen-Yi Huang, Neal D. Freedman, Lei Song, Thomas U. Ahearn, Montserrat García-Closas, Stephen J. Chanock & Mitchell J. Machiela

Department of Medicine, Queen’s University, Kingston, Ontario, Canada

Caitlyn Vlasschaert

Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Xiaoxi Liu & Chikashi Terao

Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, MD, USA

Derek W. Brown

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

Georgi Hudjashov, Valdislav Tuzov, Fanny-Dhelia Pajuste, Andres Metspalu, Tõnu Esko, Mari Nelis, Lili Milani & Reedik Mägi

Center for Data and Computational Sciences (C-DACS), VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA

Bryan R. Gorman & Saiju Pyarajan

Booz Allen Hamilton, McLean, VA, USA

Bryan R. Gorman

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

Joe Dennis, Antonis C. Antoniou, Manjeet K. Bolla, Douglas F. Easton, Kyriaki Michailidou, Paul D. P. Pharoah & Qin Wang

Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA

Weiyin Zhou

Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Yukihide Momozawa

Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Saiju Pyarajan & Po-Ru Loh

Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Fanny-Dhelia Pajuste

Division of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

Vijay G. Sankaran

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

Vijay G. Sankaran

Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA

Hanna M. Ollila

Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

Alexander Bick

Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan

Chikashi Terao

Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan

Chikashi Terao

Center for Data Sciences, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Po-Ru Loh

Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada

Irene L. Andrulis

Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Irene L. Andrulis

Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA

Hoda Anton-Culver

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK

Amy Berrington de Gonzalez

Department of Radiation Oncology, Hannover Medical School, Hannover, Germany

Natalia V. Bogdanova

Gynaecology Research Unit, Hannover Medical School, Hannover, Germany

Natalia V. Bogdanova & Thilo Dörk

N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus

Natalia V. Bogdanova

Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark

Stig E. Bojesen

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark

Stig E. Bojesen

Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Stig E. Bojesen

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany

Hermann Brenner

Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany

Hermann Brenner

German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany

Hermann Brenner

Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Jenny Chang-Claude & Rudolf Kaaks

Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Jenny Chang-Claude

Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

Georgia Chenevix-Trench

City of Hope Comprehensive Cancer Center, City of Hope, Duarte, CA, USA

Sarah V. Colonna

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA

Fergus J. Couch

Sheffield Institute for Nucleic Acids (SInFoNiA), Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK

Angela Cox

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Kamila Czene & Per Hall

Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA

Mary B. Daly

Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands

Peter Devilee

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands

Peter Devilee

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK

Alison M. Dunning, Douglas F. Easton & Paul D. P. Pharoah

School of Life Sciences, University of Westminster, London, UK

Miriam Dwek

Faculty of Medicine, University of Southampton, Southampton, UK

Diana M. Eccles

Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany

Peter A. Fasching

The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK

Olivia Fletcher

Genomic Medicine Group, International Cancer Genetics and Epidemiology Group, Fundación Pública Galega de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain

Manuela Gago-Dominguez

Department of Medicine, McGill University, Montréal, QC, Canada

Mark S. Goldberg

Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, QC, Canada

Mark S. Goldberg

Human Genotyping Unit-CeGen, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

Anna González-Neira

Team Exposome and Heredity, CESP, Gustave Roussy, INSERM, University Paris-Saclay, UVSQ, Villejuif, France

Pascal Guénel

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

Christopher A. Haiman

Department of Oncology, Södersjukhuset, Stockholm, Sweden

Per Hall

Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany

Ute Hamann

Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands

Antoinette Hollestelle

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany

Reiner Hoppe

University of Tübingen, Tübingen, Germany

Reiner Hoppe

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia

John L. Hopper & Jennifer Stone

Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland

Anna Jakubowska

Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland

Anna Jakubowska

Oncology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden

Helena Jernström

Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA

Esther M. John

Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA

Esther M. John

Institute of Biochemistry and Genetics—Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia

Elza K. Khusnutdinova

Department of Genetics and Fundamental Medicine, Ufa University of Science and Technology, Ufa, Russia

Elza K. Khusnutdinova

Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA

Cari M. Kitahara

Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA

Peter Kraft

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA

Peter Kraft & Rulla M. Tamimi

Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway

Vessela N. Kristensen

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Vessela N. Kristensen

Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium

Diether Lambrechts

VIB Center for Cancer Biology, VIB, Leuven, Belgium

Diether Lambrechts

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

Annika Lindblom

Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden

Annika Lindblom

Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland

Arto Mannermaa

Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland

Arto Mannermaa

Biobank of Eastern Finland, Kuopio University Hospital, Kuopio, Finland

Arto Mannermaa

MRC Clinical Trials Unit, Institute of Clinical Trials & Methodology, University College London, London, UK

Usha Menon

Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus

Kyriaki Michailidou

School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada

Rachel A. Murphy

Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada

Rachel A. Murphy

Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland

Heli Nevanlinna

Institute for Occupational Medicine and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Nadia Obi

Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Kenneth Offit

Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Kenneth Offit

Genome Diagnostics Program, IFOM ETS – the AIRC Institute of Molecular Oncology, Milan, Italy

Paolo Peterlongo

Department of Computational Biomedicine, Cedars-Sinai Medical Center, West Hollywood, CA, USA

Paul D. P. Pharoah

Research Centre for Genetic Engineering and Biotechnology Georgi D. Efremov, MASA, Skopje, Republic of North Macedonia

Dijana Plaseska-Karanfilska

B. Rappaport Faculty of Medicine, Technion and the Association for Promotion of Research in Precision Medicine (APRPM), Haifa, Israel

Gad Rennert

Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain

Atocha Romero

Division of Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece

Emmanouil Saloustros

Division of Molecular Pathology, The Netherlands Cancer Institute – Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands

Marjanka K. Schmidt

Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute – Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands

Marjanka K. Schmidt

Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands

Marjanka K. Schmidt

Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

Rita K. Schmutzler

Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

Rita K. Schmutzler

Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

Rita K. Schmutzler

Genetic Epidemiology Group, School of Population and Global Health, University of Western Australia, Perth, Western Australia, Australia

Jennifer Stone

Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA

Rulla M. Tamimi

Department of Population Science, American Cancer Society, Atlanta, GA, USA

Lauren R. Teras

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA

Mary Beth Terry

Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Melissa A. Troester

Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA

Celine M. Vachon

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA

Clarice R. Weinberg

Laboratory of Cancer Genetics and Tumor Biology, Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland

Robert Winqvist

Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland

Robert Winqvist

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Alicja Wolk